宋育阳，女，浙江余姚，1983年12月生，中共党员，副教授，博士生导师。
国家一级酿酒师、中国果酒科创青年高层次人才。
研究方向：葡萄酒生境下的酵母代谢；葡萄酒及果酒的工艺质量控制。
一、学习工作经历
(1)2019.09-至今，西北农林科技大学，葡萄酒学院，葡萄酒学教研室主任
(2)2018.01-至今，西北农林科技大学，葡萄酒学院，副教授
(3)2021.11-2022.11，西北农林科技大学，西北农林科技大学新农村发展研究院项目与信息办公室，副主任(多岗位锻炼)
(4)2019.11-2022.11，西北农林科技大学，葡萄酒学院，葡萄酒学党支部书记
(5)2018.07-2019.07，宁夏贺兰山东麓葡萄产业园区管委会，主任助理，党组成员(挂职)
(6)2013.03-2018.01，西北农林科技大学，葡萄酒学院，讲师
(7)2009.10--2013.03，日本北海道大学，综合化学院，获生物化学(工学)博士学位
(8)2002.09-2009.07西北农林科技大学，葡萄酒学院，获发酵工程(葡萄与葡萄酒)硕士学位、酿酒工程(葡萄与葡萄酒)学士学位
二、学术兼职与奖励
中国果酒科创青年高层次人才，陕西省女科技工作者协会理事，陕西省“巾帼最美农业科技工作者”，宁夏贺兰山东麓葡萄酒产业技术协同创新中心葡萄酒微生物方向首席专家。获“日本北海道大学杰出女子研究者奖”，陕西省杨陵示范区“三八红旗手”，西北农林科技大学“我最喜爱的老师”。
三、人才培养
1.本科教学
主要承担《葡萄酒工艺学》课程。主讲《葡萄酒工艺学》在中国大学生MOOC平台顺利上线。参与承担《葡萄酒微生物学》、《葡萄酒工艺学实验》。
2.研究生培养
《高级微生物学》、《葡萄酒学进展》等课程的教学。
四、科技工作
热烈欢迎对食品科学及葡萄酒领域感兴趣的同学考取本实验室博士、硕士研究生，以及已毕业博士同仁前往本实验开展博士后合作研究。
1.科学研究
主持项目：主持包括国家自然基金项目、国家重点研发计划子课题、陕西省重点研发计划项目、宁夏重点研发计划项目课题、企业技术服务项目、重点实验室开放课题等科研项目20项。
2.代表著作与论文
著作：
(1)《葡萄酒工艺学实验》，科学出版社(5/10)；
(2)《中国葡萄酒产业发展蓝皮书》，研究出版社(7/10)；
(3)《Corynebacterium glutamicum From Systems Biology to Biotechnological Applications》，Caister Academic Press(第九章编著)
发表论文：
[1] Rong H, Fangfang ZH, Jiao J, Song, YY*. Characterization of Trichoderma reesei endoglucanase displayed on the Saccharomyces cerevisiae cell surface and its effect on wine flavor in combination with β-glucosidase. Process Biochemistry 2023, 124, 140-149.
[2] Rong H, Jiao J, Ying S, Song, YY*. Microbial community succession and volatile compounds changes during spontaneous fermentation of Cabernet Sauvignon ( Vitis vinifera L.) under rain-shelter cultivation. Food Chemistry: X 2023, 17 (10): 100618.
[3] Rong Huang, Lei Shen, Hongfei Yu, Jiao Jiang, Yi Qin, Yanlin Liu, Jin Zhang, Song, YY*. Evaluation of rain-shelter cultivation mode effects on microbial diversity during Cabernet Sauvignon (Vitis vinifera L.) maturation in Jingyang, Shaanxi, China. Food Research International. 2022
[4] Rong H, Hongfei Y, Jiao J, Song, YY*. Correlations between microbial diversity, monomeric phenols, and biological parameters during spontaneous fermentation of Cabernet Sauvignon grapes obtained from rain-shelter cultivation. LWT-Food Science and Technology 2022, 171 (15): 114146.
[5] Rong Huang, Fangfang Zhang, Xingmin Yan, Yi Qin, Jiao Jiang, Yanlin Liua, Song, YY*. Characterization of the β-Glucosidase Activity in indigenous yeast isolated from wine regions in China. Journal of Food Science. 2021.
[6] Lu, Y#, Song, YY#,Zhu, J, Xu, XG, Pang, B, Jin, H, Jiang, CM, Liu, YL, Shi, JL. Potential application of CHS and 4CL genes from grape endophytic fungus in production of naringenin and resveratrol and the improvement of polyphenol profiles and flavour of wine. 2020.
[7] Zhang, Y, Min, Z, Qin, Y, Ye, DQ, Song, YY*, Liu, YL *. Efficient Display of Aspergillus niger beta-Glucosidase on Saccharomyces cerevisiae Cell Wall for Aroma Enhancement in Wine, Journal of Agricultural and Food Chemistry. 2019, 67(18): 5169-517.
[8] Feng L, Jia H, Wang JM, Qin Y, Liu YL*, Song YY*. Selection of Indigenous Saccharomyces cerevisiae Strains for Winemaking in Northwest China. American Journal of Enology and Viticulture, 2019, 70(2): 115-126.
[9] Song, YY, Zhang Yujie, Liu Ning, Ye Dongqing, Gong Xue, Qin Yi, Liu Yanlin*. Evaluation of volatiles of wild strawberry and impact odorants of strawberry wines at different stage of fermentation in southern Shaanxi, China. International Journal of Food Properties. 2017, 20:399-415.
[10] Su BF, Xue JR, Xie CY, Fang YL, Song, YY*, Sigfredo F. Digital surface model applied to unmanned aerial vehicle based photogrammetry to assess potential biotic or abiotic effects on grapevine canopies. International Journal of Agricultural and Biological Engineering. 2016, 9(6):119-130.
[11] Liu Ning#, Song YY#, Dang Guofang, Ye Dongqing, Liu Yanlin*. Effect of Wine Closures on the Aroma Properties of Chardonnay Wines after Four Years of Storage. South African Journal of Enology and Viticulture. 2015, 3(36):296-303.
[12] Liu Ning, Qin Yi, Song, YY, Tao Yong Sheng, Sun Yue, Liu Yanlin*. Aroma composition and sensory quality of Cabernet Sauvignon wines fermented by indigenous S. cerevisiae strains in the eastern base of the Helan Mountain (China). International Journal of Food Properties, 2016, (19):2417-2431.
[13] Jiao Jian, Ma Yaner, Chen Sha, Liu Chonghuai, Song, YY, Qin Yi, Yuan Chunlong, Liu Yanlin*. Melatonin-Producing Endophytic Bacteria from Grapevine Roots Promote the Abiotic Stress-Induced Production of Endogenous Melatonin in Their Hosts. Frontiers in Plant Science, 2016, 7(3):1-13.
[14] Song, YY, John Masani Nduko, Ken’ichiro Matsumoto, Seiichi Taguchi. Corynebacterium glutamicum : From Systems Biology to Biotechnological Applications (Chapter: 9 Microbial factory for the production of polyesters: A new platform of Corynebacterium glutamicum) Caister Academic Press, 137-148, May 2015.
[15] Liu Ning, Qin Yi, Song, YY, Ye Dongqin, Yuan Wei, Pei Yingfang, Xue Bo, Liu Yanlin*.Selection of indigenous Saccharomyces cerevisiae strains in Shanshan County (Xinjiang, China) for winemaking and their aroma-producing characteristics. World Journal of Microbiology and Biotechnology, 2015, 31(11): 1781-1792.
[16] Liu Ning, Song, YY, Qin Yi, Gong xue, Liu Yanlin*. Chromatic Characteristics and Anthocyanin Compositions of Cabernet Sauvignon Wines: Influence of Indigenous Saccharomyces cerevisiae Strains in Ningxia, China. Food Science and Biotechnology, 2015, 24(6): 1973-1978.
[17] Ken’ichiro Matsumoto, Kota Tobitani, Shunsuke Aoki, Song, YY, Toshihiko Ooi, Seiichi Taguchi. Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step. AMB Express 2014,4:83.
[18] Song, YY, Ken’ichiro Matsumoto, Tsutomu Tanaka, Akihiko Kondo, Seiichi Taguchi. Single-step production of polyhydroxybutyrate from starch by using α-amylase cell-surface displaying system of Corynebacterium glutamicum. J. Biosci. Bioeng. 2013, 115(1), 12-14.
[19] Ken’ichiro Matsumoto, Satsuki Terai, Ayako Ishiyama, Jian Sun, Taizo Kabe, Song, YY, John Masani Nduko, Tadahisa Iwata, Seiichi Taguchi. One-pot microbial production, mechanical properties, and enzymatic degradation of isotactic P[(R)-2-hydroxybutyrate] and its copolymer with (R)-lactate. Biomacromolecules. 2013,14(6):1913-1918.
[20] Song, YY, Ken’ichiro Matsumoto, Miwa Yamada, Aoi Gohda, Christopher J. Brigham, Anthony J. Sinskey, Seiichi Taguchi. Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production. Appl Microbiol Biotechnol 2012, 93,1917–1925.
[21] Ken’ichiro Matsumoto, KeiKitagawa, Sung-JinJo, Song, YY, SeiichiTaguchi. Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Corynebacterium glutamicum using propionate as a precursor. J. Biotechnol 2011, 152, 144-146.
[22] Fumi Shozui, Jian Sun, Song, YY, Miwa Yamada, Kohei Sakai, Ken’ichiro Matsumoto, Kazuma Takase, Seiichi Taguchi. A new beneficial mutation in pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template. Biosci Biotechnol Biochem 2010, 74, (8), 1710-1712.
[23] 刘俊丽, 孙广玲, 黄蓉, 刘延琳, 姜娇, 宋育阳*. 微通氧条件下东方伊萨酵母对猕猴桃酒的降酸效果[J]. 中国食品学报,2023,23(4):283-294.
[24] 刘俊丽, 吴迪, 高蕾, 姜娇, 宋育阳*. 鲜食红地球葡萄蒸馏酒的酿造工艺研究[J]. 中国食品学报,2023,23(2):142-153.
[25] 董超,黄蓉,姜娇，秦义,刘延琳,宋育阳*. 粟酒裂殖酵母和戴尔有孢圆酵母混合发酵对赤霞珠桃红葡萄酒品质的影响[J]. 中国食品学报,2023,23(3):206-216.
[26] 孙广玲, 刘俊丽, 吴迪, 刘雨新, 姜娇, 宋育阳*. 东方伊萨酵母羧酸转运蛋白基因的表达及功能验证[J]. 中国食品学报,2023,23(2):48-60.
[27] 黄蓉,董超,姜娇,宋育阳*. 避雨栽培对'赤霞珠'葡萄果表微生物多样性的影响[J]. 园艺学报,2023,50(3):635-646.
[28] 吴迪,程艺超,姜娇,宋育阳*. 酵母中葡萄糖阻遏作用机制研究进展[J]. 微生物学报,2023,63(9):3409-3427.
[29] 黄蓉,吕林灿,李莹,宋育阳*. 酿酒酵母表面展示金属硫蛋白吸附葡萄酒中铜离子的研究. 中国食品学报2022, 22 (7).
[30] 耿仕瑾，姜 娇，曲 睿，石 侃，秦 义，刘延琳，宋育阳*. 戴尔有孢圆酵母调控晚采小芒森葡萄酒乙酸和香气的研究. 农业工程学报. 2021.37(7), 293-300.
[31] 黄蓉,董超,余鸿飞,宋育阳*. 酿酒酵母表面展示技术表达酸性蛋白酶. 中国食品学报2021, 22 (2).
会议论文
1.Song YY. Expression of wine-related enzymes utilising cell surface display technology, 口头报告, 37th International Specialised Symposium on Yeasts (ISSY 2023), 2023
2.Rong H, Song YY. Evaluation of the Microbial Diversity of Cabernet Sauvignon during Grape Maturation under Rain-shelter Cultivation Mode | Poster | June, 2021-The 72nd ASEV (American Society for Enology and Viticulture) National Conference, June 21-24.
3.Rong H, Song YY. Study on Expression of Acid Protease Using Saccharomyces cerevisiae Surface Display Technology | Poster and Flash Talk | June, 2021-The 72nd ASEV (American Society for Enology and Viticulture) National Conference, June 21-24.
4.Song YY, 避雨栽培对赤霞珠葡萄相关的微生物群落和葡萄酒的影. 13th International Seminar on Viticulture and Enology. 2023年04月20日-2023年04月22
5.Song YY, Matsumoto K, Yamada M, Gohda A, Taguchi S. A novel microbial production system for lactate-based polyester. Paper No: PBi-21, The 5th GCOE International Symposium, Hokkaido University, Sapporo, 2012.02, 口头报告.
6.Song YY, Matsumoto K, Yamada M, Gohda A, J. Brigham C, J. Sinskey A, Taguchi S. Direct conversion of glucose into lactate-based polyesters using engineered Corynebacterium glutamicum as a whole cell catalyst. Paper No: BIOT308, 243rd ACS National Meeting, San Diego, USA, 2012.03, 口头报告.
7.Song YY, Matsumoto K, Yamada M, Taguchi S. Engineered Corynebacterium glutamicum as an endotoxin-free platform for lactate-based polyester production. Paper No: AB1-08, The 12th Japan-China-Korea Joint Symposium on Enzyme Engineering, Kanazawa, 2012.05, 口头报告.
8.Song YY, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of lactate-based polyesters in metabolically engineered Corynebacterium glutamicum . Paper No: O-S2-0061, 15th International Biotechnology Symposium and Exhibition, Daegu, Korea, 2012.09, 口头报告.
9.Song YY, Matsumoto K, Yamada M, Gohda A, Taguchi S. Biosynthesis of lactate-based polyester in food-grade bacterium. Paper No: No.P31, 高分子学会北海道支部研究発表会, 札幌, 2012.01, 口头报告.
10.Song YY, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of lactate-based polyester using engineered Corynebacterium glutamicum as a whole cell catalyst. International Symposium on Biopolymers, Cairns, Australia, 2012.10, 口头报告.
11.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Production of poly(lactate-co-3-hydroxybutyrate) in recombinant Corynebacterium glutamicum expressing lactate-polymerizing enzyme. Paper No: IN-26, 2011 Taiwan-Japan Bilateral Polymer Symposium, Taiwan, 2011.09, 口头报告.
12.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of poly(lactate-co-3-hydroxybutyrate) in endotoxin-free Corynebacterium glutamicum expressing lactate-polymerizing enzyme. Paper No: No.2Ka02, 日本生物工学会大会, 東京, 2011.09, 口头报告.
13.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Production of endotoxin-free lactate(LA)-based polyesters in recombinant Corynebacterium glutamicum. Paper No: 2C01p14 日本農芸化学会大会, 京都, 2011.03, 口头报告.
14.Song YY, Matsumoto K, Taguchi S. Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Corynebacterium glutamicum using propionate as a precursor. Paper No: 11, 平成22年度第一回合同学術講演会, Sapporo, 2010.07, 口头报告.
15.Nduko J M, Matsumoto K, Song YY, Taguchi S. Microbial plastic factory: synthesis and properties of the new lactate-based and related biopolymers. Paper No: POLY72, 244th ACS National Meeting & Exposition, Philadelphia, USA, 2012.08, 口头报告.
16.津田春奈, 宋育阳, 松本謙一郎, 大井俊彦, 近藤昭彦, 田口精一. Corynebacterium glutamicum の細胞表層提示技術を用いたデンプンからのポリヒドロキシブタン酸(PHB)の直接生産. Paper No: 2C01p05, 日本農芸化学会大会, 京都, 2012.03,
17.渡辺剛志, 宋育阳, 松本謙一郎, 大井俊彦, 田口精一. アセトアセチルCoAレダクターゼ高活性変異体の解析とそれを用いたCorynebacterium glutamicumによるPHB生産の増強. Paper No: 2C01p06, 日本農芸化学会大会, 京都, 2012.03,
18.Watanabe T, Song YY, Matsumoto K, Ooi T, Taguchi S. Enhanced polyhydroxybutyrate production by highly active mutant of acetoacetyl-CoA reductase in Corynebacterium glutamicum. Paper No: PBi-09, The 5th GCOE International Symposium, Hokkaido University, Sapporo, 2012.02, 口头报告.
五、实验室简介
实验室为国家葡萄产业体系刘延琳教授课题组实验室。实验室为陕西省葡萄与葡萄酒重点实验室、国家林草局葡萄与葡萄酒工程技术研究中心、陕西省特色果品定向设计加工工程技术研究中心、陕西省葡萄与葡萄酒工程技术研究中心组成单元。团队获批校级优秀教学团队，校级优秀导师团队。
实验室培养毕业生多数进入食品相关科研院所或企事业单位工作、学习，包括西北农林科技大学、华东理工大学、山西农业大学、宁夏大学、茅台学院等，培养毕业硕士前往澳大利亚阿德莱德大学、上海交通大学、中国农业大学等攻读博士学位。团队旨在创造具有多层次的研究生学术培养环境，培养优秀的科学和行业人才。
